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Anthropic expands Claude for healthcare and life sciences with Opus 4.5, new connectors and HIPAA‑ready tools

Anthropic announced on Jan 11, 2026 that it is extending Claude’s capabilities for healthcare and life sciences with a new Claude for Healthcare suite, expanded life‑sciences connectors, and model improvements in Claude Opus 4.5.

Anthropic expands Claude for healthcare and life sciences with Opus 4.5, new connectors and HIPAA‑ready tools

On Jan 11, 2026 Anthropic announced a set of expansions for Claude aimed at healthcare and life sciences users: a new Claude for Healthcare suite, additional life‑sciences connectors, and the rollout of the latest model, Claude Opus 4.5. The company says these additions make Claude more practically useful for clinical operations, regulatory work, and for individuals seeking help understanding personal health data. Some enterprise offerings are described as HIPAA‑ready for providers and payers.

Model improvements: Opus 4.5 and benchmark results

Anthropic reports measurable gains in Claude’s general capabilities and evaluates progress using medical and scientific task simulations. Key points from the announcement:

  • Claude Opus 4.5 shows improved accuracy on critical life‑sciences tasks such as scientific figure interpretation, computational biology, and protein understanding.
  • The SpatialBench evaluation by LatchBio (Dec 2025) included 146 verifiable problems across five spatial problem types and seven task categories; Anthropic notes that Opus 4.5 models were evaluated with extended thinking (64k tokens) and native tool use.
  • Opus 4.5 also performs better on Anthropic’s internal honesty evaluations, indicating reductions in factual hallucinations when using extended thinking.

Anthropic argues these model improvements translate into real‑world gains: speeding prior authorization reviews, easing clinician administrative burden, and helping prepare regulatory submissions so therapies can reach patients faster.

Claude for Healthcare: what’s new

The Claude for Healthcare package is presented as a complementary toolset enabling healthcare providers, payers, and health tech companies to use Claude for medical purposes with HIPAA‑ready products. Notable additions include connectors that let Claude pull data from standard industry systems and new Agent Skills.

New connectors

Claude can now connect to a range of healthcare databases to make relevant information easier to find and use:

  • Centers for Medicare & Medicaid Services (CMS) Coverage Database, including Local and National Coverage Determinations — supports locally accurate coverage checks, prior authorization validation, and claim appeal generation.
  • International Classification of Diseases, 10th Revision (ICD‑10) — lookup of diagnosis and procedure codes to support coding, billing accuracy and claims management; data provided by CMS and CDC.
  • National Provider Identifier Registry — supports provider verification, credentialing and directory management.

HIPAA‑compliant organizations using Claude for Enterprise can also access existing healthcare connectors such as PubMed (more than 35 million items of biomedical literature) for up‑to‑date research and literature reviews.

New Agent Skills

Anthropic added a FHIR development skill to improve interoperability by helping developers connect systems faster, plus a sample prior authorization review skill that organizations can customize to their policies. The prior authorization skill cross‑references coverage rules, clinical guidelines, patient records and appeal documents to produce review templates.

Example healthcare use cases

Anthropic lists several practical uses:

  • Speeding prior authorization reviews by aggregating coverage requirements (from CMS or custom policies), checking clinical criteria against patient records in a HIPAA‑ready way, and generating a proposed determination with supporting materials.
  • Supporting claims appeals by assembling evidence from patient records, policies, clinical guidelines and prior documentation to strengthen provider appeals and help payers process them faster.
  • Coordinating care and triaging patient messages by sorting portal messages, referrals and handoffs to identify urgent items.
  • Enabling startups to build products on the Claude Developer Platform for tasks such as ambient scribing or chart reviews to reduce administrative burden.

Connecting personal health data

In the US, Claude Pro and Max subscribers can opt to give Claude secure access to lab results and health records. New HealthEx and Function connectors are available in beta now; Apple Health and Android Health Connect integrations are rolling out in beta this week via the Claude iOS and Android apps.

When connected, Claude can summarize medical history, explain test results in plain language, detect patterns across fitness and health metrics, and prepare questions for appointments. Integrations are private by design: users choose what to share, must explicitly opt in, can edit or revoke permissions at any time, and Anthropic states it does not use health data to train models. Claude includes contextual disclaimers, acknowledges uncertainty, and directs users to healthcare professionals for personalized guidance.

Expanding Claude for Life Sciences

Anthropic is broadening Claude’s life‑sciences feature set beyond preclinical R&D toward clinical trial operations and regulatory workflows. New connectors include:

  • Medidata — Medidata Study Feasibility customers can let Claude access historical trial enrollment and site performance data.
  • ClinicalTrials.gov — access to trial registry information to support development pipelines, recruitment planning, site selection and protocol design.
  • ToolUniverse — a library of over 600 vetted scientific tools for rapid hypothesis testing and analysis.
  • bioRxiv & medRxiv — preprint servers to surface the latest research before formal publication.
  • Open Targets and ChEMBL — databases for target identification and bioactive compounds in early discovery.
  • Owkin — Pathology Explorer agent for tissue image analysis and tumor mapping.

These join existing Life Sciences connectors such as Benchling, 10x Genomics, PubMed, BioRender, Synapse.org and Wiley Scholar Gateway. The Benchling connector is now also available via Claude.ai on the web, with secure SSO access in addition to the desktop app.

Anthropic also added Agent Skills for scientific problem selection, converting instrument data to the Allotrope format, and bioinformatics bundles (scVI‑tools and Nextflow deployment). A sample skill for drafting clinical trial protocols includes endpoint recommendations and considers regulatory pathways, competitive landscape and relevant FDA guidance.

Example life‑sciences use cases

  • Drafting clinical trial protocols that account for FDA and NIH requirements and organization templates.
  • Monitoring clinical trial operations (enrollment and site performance) using Medidata data to surface issues early.
  • Preparing regulatory submissions by identifying gaps in documentation, drafting agency responses, and navigating FDA guidelines.

Customers, partners and ecosystem

Anthropic cites user feedback from partners including Banner Health, Novo Nordisk, Qualified Health, Genmab, Sanofi, Elation Health, Edison Scientific, Viz.ai, Flatiron Health, Veeva AI, Heidi Health, Schrödinger, Premier, Commure, Carta Healthcare and Brellium. The company notes Claude is available on AWS, Google Cloud and Microsoft, and it partners with systems integrators and consultancies such as Accenture, Deloitte, KPMG, PwC and others to help organizations adopt Claude for specialist work.

Availability and next steps

The new connectors and Agent Skills are generally available to Claude subscribers (Claude Pro, Max, Teams and Enterprise). Anthropic provides tutorial guides and sales contacts for organizations that want to deploy Claude internally.

Footnotes and changelog

  • Anthropic refers to the Claude Opus 4.5 system card (see pages 48–49).
  • Changelog: on February 7, 2026 the introductory paragraph was edited to clarify that HIPAA‑ready products are specific to healthcare providers and payers, while personal health integrations for individual users are covered in the “Connecting personal health data” section.